M1, a Subdivision of the Human Blood-Group Antigen M

Blood Group Antigen Recognition via the Group A Streptococcal M Protein Mediates Host Colonization

Streptococcus pyogenes (group A streptococcus [GAS]) is responsible for over 500,000 deaths worldwide each year. The highly virulent M1T1 GAS clone is one of the most frequently isolated serotypes from streptococcal pharyngitis and invasive disease. The oral epithelial tract is a niche highly abundant in glycosylated structures, particularly those of the ABO(H) blood group antigen family. Using...

The Tall Tale of the Helicobacter pylori Blood Group Antigen Binding Proteins

  The features of Helicobacter pylori adhesins, their interactions with their host counterparts, regulated and selective gene expressions are amongst the many clever strategies this microorganism undertakes to survive the otherwise sterile gastric milieu. The ingenious crafting of these interactions and the respective host reactions govern, in part, an array of consequences ranging from asympto...

Monoclonal antibodies directed against the human Leb blood group antigen.

Four monoclonal antibodies produced by hybridomas obtained from a mouse immunized with a human adenocarcinoma cell line SW1116 (Koprowski, H., Steplewski, Z., Mitchell, K., Herlyn, M., Herlyn, D., and Fuhrer, P. (1979) Somatic Cell Genet. 5, 957-972) are directed against the Leb antigen of the human Lewis blood group system. Their specificities were established by binding studies using purified...

Preservation of M. gallisepticum Antigen

Eternal m-security subdivision numbers in graphs

An eternal $m$-secure set of a graph $G = (V,E)$ is aset $S_0subseteq V$ that can defend against any sequence ofsingle-vertex attacks by means of multiple-guard shifts along theedges of $G$. A suitable placement of the guards is called aneternal $m$-secure set. The eternal $m$-security number$sigma_m(G)$ is the minimum cardinality among all eternal$m$-secure sets in $G$. An edge $uvin E(G)$ is ...